The 49ers and Lions are two of the most efficient offenses in the NFL in 2024. Detroit ranks second in the league in yards per play (6.1), while San Francisco ranks fourth (6.1). The potential for fireworks offers the rare potential for variance in your NFL DFS lineups for Monday Night Football. Both offenses are capable of moving the ball from a variety of personnel settings, which means there is plenty of value in the NFL DFS player pool. Who should you target for 49ers vs. Lions DFS picks and which highly-rostered players should you avoid? Before locking in any NFL DFS picks on sites like DraftKings and FanDuel for Monday Night Football, be sure to check out the NFL DFS advice, strategy, and stacks from SportsLine daily Fantasy expert Mike McClure.
McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings. Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him is way up.
Now, McClure has turned his attention to Lions vs. Niners on Monday Night Football and just locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.
Top NFL DFS picks for Lions vs. 49ers
One of McClure’s top NFL DFS picks for Monday Night Football is 49ers tight end George Kittle. In a season where Deebo Samuel has been inconsistent while Christian McCaffrey and Brandon Aiyuk have been injured, Kittle has been the one near-constant for the San Francisco offense. He’s 43 yards shy of his fourth career 1,000-yard season and his eight touchdowns rank second among NFL tight ends behind only Mark Andrews.
Kittle is coming off an eight-catch, 106-yard performance in a loss to the Dolphins last week and he’s now reached at least 20 points on DraftKings seven times this season. Detroit ranks 27th in the NFL against the pass this year and Kittle’s 3.03 yards per route run are the most at his position. He’s also been targeted 20 times in the red zone (second among TEs) and has a 32.8% red-zone target share, so he’s likely to see high-quality targets in addition to volume on Monday. See who else to roster here.
He’s also targeting Lions running back Jahmyr Gibbs. With David Montgomery (knee) out last week, Gibbs piled up a season-high 27 touches and produced 153 scrimmage yards and a touchdown against Chicago. He notched his third 100-yard rushing game of the year and has now scored 15 total touchdowns this year.
Because of the work split throughout the season with Montgomery, Gibbs ranks 28th among running backs in the NFL in snap share (55.0%) and 33rd in opportunity share (51.0%) but he still ranks seventh in the NFL in rushing and fourth among RBs in receiving yards. Meanwhile, he’s second to only Derrick Henry in touchdowns this season and you can expect him to continue to make the most of more opportunities with the Lions battling for home-field advantage and Montgomery out again this week. See who else to roster here.
How to set NFL DFS lineups for Monday Night Football
McClure is targeting another undervalued player who could explode for huge numbers on Monday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of McClure’s NFL DFS picks, at SportsLine.
So who is Mike McClure including in his optimal NFL DFS lineups for Monday Night Football, and which under-the-radar player offers huge value? Visit SportsLine now to see optimal NFL DFS picks, NFL DFS rankings, NFL DFS advice and NFL DFS stacks, all from a daily Fantasy expert with more than $2 million in winnings, and find out.
